Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800312 | 0.86 | IDO1 (0.58) | IDO1CFTRMEN1KMT2AKDM4E | |
| SCHEMBL11794065 | 0.83 | IDO1 (0.54) | IDO1CFTRMEN1KMT2AKDM4E | |
| SCHEMBL11686483 | 0.83 | IDO1 (0.59) | IDO1KMT2AKDM4EPOLB | |
| SCHEMBL11988856 | 0.79 | IDO1 (0.68) | IDO1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL24451031 | 0.78 | IDO1 (0.61) | IDO1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24508233 | 0.77 | MEN1 (0.44) | IDO1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11800257 | 0.77 | IDO1 (0.51) | IDO1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30598338 | 0.76 | SMN1; SMN2 (0.55) | CFTRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL538290 | 0.76 | SMN1; SMN2 (0.55) | CFTRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8006518 | 0.76 | IDO1 (1.00) | IDO1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223786-B2 | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-29 | — | — | US | disclosed |
| US-20060111415-A1 | 2-Aminonaphthalene derivatives and related glycogen phosphorylase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111415-A1 | 2-Aminonaphthalene derivatives and related glycogen phosphorylase inhibitors | PYGM, GYS1, PYGL | IDO1 2919/4885CFTR 4758/4885MEN1 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.