Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901174 | 0.74 | LMNA (0.73) | KMT2ALMNAL3MBTL1 | |
| SCHEMBL1516167 | 0.71 | EPHX2 (1.00) | EPHX2MEN1KMT2AMAPTHTT | |
| SCHEMBL10054999 | 0.71 | EPHX2 (0.92) | EPHX2MEN1KMT2AMAPTBCHE | |
| SCHEMBL1689206 | 0.70 | EPHX2 (0.68) | EPHX2MEN1KMT2AL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL27735879 | 0.70 | EPHX2 (0.96) | EPHX2MEN1KMT2AMAPTHTT | |
| SCHEMBL3342586 | 0.68 | L3MBTL1 (0.80) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL25737005 | 0.68 | EPHX2 (0.76) | EPHX2MEN1KMT2ALMNAMAPT | |
| SCHEMBL5623718 | 0.68 | CYP1A2 (0.65) | EPHX2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27262317 | 0.67 | EPHX2 (0.58) | EPHX2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL5143683 | 0.67 | EPHX2 (0.63) | EPHX2MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132179-A2 | THERAPEUTICS COMPRISING PYRIDINIUM DERIVATIVES | UNIVERSITY OF BATH (GB) | 2007-11-22 | — | — | WO | disclosed |