Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616327 | 0.85 | ESR1 (0.40) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL3023143 | 0.85 | ESR1 (0.61) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL29459439 | 0.83 | ESR1 (0.62) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL298390 | 0.83 | ESR1 (0.62) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL3809453 | 0.83 | ESR2 (0.48) | ESR1ESR2 | |
| SCHEMBL10939878 | 0.78 | ESR1 (0.61) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL5386114 | 0.78 | ESR1 (0.71) | ESR1ESR2LMNA | |
| SCHEMBL17532651 | 0.78 | TRPA1 (0.40) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL5386081 | 0.77 | GABRA1 (0.49) | ESR1ESR2GABRA1GABRB2HSP90AA1 | |
| SCHEMBL16581349 | 0.75 | ESR1 (0.39) | ESR1ESR2HSP90AA1HSP90AB1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9122147-B2 | Pattern forming process | SHIN-ESTU CHEMICAL CO., LTD. (JP) | 2015-09-01 | — | — | US | disclosed |
| US-9122147-B2 | Pattern forming process | SHIN-ESTU CHEMICAL CO., LTD. (JP) | 2015-09-01 | — | — | US | disclosed |
| US-20140235057-A1 | PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235057-A1 | PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | DBF4, DCUN1D4, SDC4 | ESR1 1397/4885ESR2 2548/4885GABRA1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.