Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839880 | 0.86 | PDE2A (0.50) | HSD17B1HSD17B2KDM4ENQO2PDE2A | |
| SCHEMBL23174675 | 0.84 | HSD17B1 (0.35) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL17696924 | 0.84 | TSHR (0.43) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL27495808 | 0.84 | PDE2A (0.48) | HSD17B1HSD17B2KDM4ENQO2PDE2A | |
| SCHEMBL3681247 | 0.82 | ESR1 (0.52) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL29404893 | 0.82 | ESR1 (0.52) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL4470436 | 0.79 | ESR1 (0.52) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL544510 | 0.79 | ESR1 (0.61) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL29372911 | 0.79 | ESR1 (0.61) | HSD17B1HSD17B2ESR1ESR2HSD17B10 | |
| SCHEMBL30249992 | 0.79 | ALDH1A1 (0.64) | HSD17B1HSD17B2ESR1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936739-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-30 | — | — | US | claimed |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-01-09 | — | — | US | claimed |
| EP-1262471-A2 | Fluorine-containing bisphenols, their preparation, intermediates towards their preparation, and their use | BAYER AG (DE) | 2002-12-04 | — | — | EP | claimed |
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2007-11-22 | — | — | US | disclosed |
| US-7268260-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-11 | — | — | US | disclosed |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2006-11-30 | — | — | US | disclosed |
| US-7112704-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6936739-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| EP-1262471-A2 | Fluorine-containing bisphenols, their preparation, intermediates towards their preparation, and their use | BAYER AG (DE) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | CYP4F2, CYP4F12, CYP4F3 | HSD17B1 501/4885HSD17B2 249/4885ESR1 1252/4885 |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | HSD17B1 194/4885HSD17B2 108/4885ESR1 21/4885 |
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | HSD17B1 194/4885HSD17B2 108/4885ESR1 21/4885 |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP2F1, HNF4A, FLI1 | HSD17B1 148/4885HSD17B2 178/4885ESR1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.