Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704203 | 0.79 | ALDH1A1 (0.38) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL704697 | 0.79 | ALDH1A1 (0.38) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL7979936 | 0.78 | NAAA (0.32) | ALDH1A1TSHRHSD17B10NAAA | |
| SCHEMBL705062 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL712068 | 0.75 | NAAA (0.37) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL5398949 | 0.75 | ALDH1A1 (0.35) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL5391570 | 0.75 | ALDH1A1 (0.35) | ALDH1A1NAAATDP1FFAR3 | |
| SCHEMBL338659 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10NAAATDP1 | |
| SCHEMBL5395132 | 0.71 | ALDH1A1 (0.32) | ALDH1A1TSHRNAAA | |
| SCHEMBL5388576 | 0.71 | CYP2C19 (0.35) | ALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| EP-1473296-B1 | Organofunctional surface modified metal oxides | WACKER CHEMIE AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1473296-A1 | Organofunctional surface modified metal oxides | Wacker-Chemie GmbH (DE) | 2004-11-03 | — | — | EP | disclosed |