Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411225 | 0.90 | RIPK3 (0.37) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL5399439 | 0.87 | SLC22A12 (0.38) | SLC22A12 | |
| SCHEMBL5398430 | 0.78 | KDM4E (0.42) | SMN1; SMN2KDM4EMAPK1ALDH1A1 | |
| SCHEMBL5405487 | 0.77 | MEN1 (0.36) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL5415082 | 0.75 | SLC16A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5397504 | 0.74 | ALDH1A1 (0.36) | SMN1; SMN2KDM4EMAPK1ALDH1A1 | |
| SCHEMBL5395357 | 0.73 | PDE5A (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5398855 | 0.72 | — | — | |
| SCHEMBL5396019 | 0.71 | TBXAS1 (0.38) | TBXAS1 | |
| SCHEMBL5404073 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |