Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399439 | 0.91 | SLC22A12 (0.38) | — | |
| SCHEMBL5408105 | 0.87 | SLC16A1 (0.36) | — | |
| SCHEMBL5411225 | 0.87 | RIPK3 (0.37) | MEN1KMT2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL5403374 | 0.77 | SLC22A12 (0.38) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL5396019 | 0.76 | TBXAS1 (0.38) | — | |
| SCHEMBL5397504 | 0.76 | ALDH1A1 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL5398848 | 0.76 | PDE1A (0.37) | — | |
| SCHEMBL5413292 | 0.75 | SLC16A1 (0.33) | — | |
| SCHEMBL5415082 | 0.74 | SLC16A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5402899 | 0.74 | PDE1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |