SCHEMBL5403699

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14457104	0.86	ALDH1A1 (0.43)	PGRALDH1A1NPC1PLA2G1BNFKB1
	SCHEMBL4426124	0.78	PGR (0.62)	PGRALDH1A1TDP2MEN1KMT2A
	SCHEMBL3368868	0.77	PGR (0.69)	PGRALDH1A1KDM4ECA1CA9
	SCHEMBL13113557	0.75	PGR (0.55)	PGRALDH1A1KDM4EHPGDTDP1
	SCHEMBL388355	0.75	PGR (0.55)	PGRALDH1A1KDM4ECA1CA9
	SCHEMBL20951359	0.75	PGR (0.55)	PGRALDH1A1NPC1PLA2G1BRAB9A
	SCHEMBL3361527	0.75	PGR (0.55)	PGRALDH1A1TDP2KDM4ECA1
	SCHEMBL192717	0.75	PGR (0.69)	PGRTDP2MEN1KMT2A
	SCHEMBL14827606	0.73	HDAC3 (0.44)	PGRALDH1A1NPC1PLA2G1BNFKB1
	SCHEMBL4420953	0.72	PGR (0.77)	PGRALDH1A1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.