SCHEMBL5492827

SCHEMBL5492827

Cc1cc(CCl)ccc1-c1ccc(CCl)cc1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
TTR P02766 3/20 0.35
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
SKP2 Q13309 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CSNK2A1 P68400 2/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A3 Q8NEV1 1/20 0.31
NSD2 O96028 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15063371 0.87 RARB (0.39) ESR1ESR2
SCHEMBL21753344 0.83 CYP17A1 (0.38)
SCHEMBL540384 0.82 ALDH1A1 (0.40) ESR1ESR2TTRKDM4ECYP3A4
SCHEMBL29377856 0.82 ALDH1A1 (0.40) ESR1ESR2TTRKDM4ECYP3A4
SCHEMBL21753348 0.80 TDO2 (0.38) CYP2C19PTGS1PTGS2CA1CA2
SCHEMBL19512351 0.80 ALDH1A1 (0.39) ESR1ESR2TTRKDM4ECYP3A4
SCHEMBL1291043 0.78 TTR (0.40) ESR1ESR2TTRKDM4ECYP3A4
SCHEMBL6914100 0.78 ESR1 (0.37) ESR1ESR2TTRKDM4ECYP3A4
SCHEMBL27282332 0.78 LTA4H (0.40) KDM4EPTGS1PTGS2
SCHEMBL21753328 0.76 KDM4E (0.44) KDM4EHIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029270-B2 Phenolic resin composition, and methods for manufacturing cured relief pattern and semiconductor ASAHI KASEI E-MATERIALS CORPORATION (JP) 2015-05-12 US disclosed
US-20130168829-A1 PHENOLIC RESIN COMPOSITION, AND METHODS FOR MANUFACTURING CURED RELIEF PATTERN AND SEMICONDUCTOR ASAHI KASEI E-MATERIALS CORPORATION (JP) 2013-07-04 US disclosed
US-7227027-B2 Carbazole derivative and its use in electroluminescent devices TSINGHUA UNIVERSITY (CH) 2007-06-05 US disclosed
US-20050127826-A1 Carbazole derivative and its use in electroluminescent devices BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050127826-A1 Carbazole derivative and its use in electroluminescent devices OCIAD1, OCIAD2, EED ESR1 156/4885ESR2 153/4885TTR 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.