Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29556732 | 1.00 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7937688 | 0.96 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28634670 | 0.89 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL30103334 | 0.82 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL524602 | 0.82 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9861299 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL29546213 | 0.81 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4832744 | 0.81 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL2877998 | 0.80 | PNMT (0.61) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL27365007 | 0.77 | PGR (0.42) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | claimed |
| CN-114539478-A | Preparation method of comb-shaped polyolefin thermoplastic elastomer based on feeding strategy regulation and control | 浙江大学衢州研究院 | 2022-05-27 | — | — | CN | claimed |
| CN-114539477-A | Preparation method of ethylene propylene diene monomer | 浙江大学衢州研究院 | 2022-05-27 | — | — | CN | claimed |
| US-20040054100-A1 | Production of polyropylene | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2004-03-18 | — | — | US | claimed |
| EP-0604908-B1 | Process for the polymerisation of alpha-olefins using metallocene compounds having ligands of fluorenylic type | BASELL TECHNOLOGY CO BV (NL) | 2001-09-19 | — | — | EP | claimed |
| JP-7002935-A | — | — | None | — | — | JP | disclosed |
| EP-3584075-B1 | LAMINATE | MITSUI CHEMICALS INC (JP) | 2024-06-05 | — | — | EP | disclosed |
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | disclosed |
| US-20230174758-A1 | POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THEM | JAPAN POLYPROPYLENE CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| EP-4159903-A1 | HEAT STORAGE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-04-05 | — | — | EP | disclosed |
| EP-4159439-A1 | POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THESE | Japan Polypropylene Corporation (JP) | 2023-04-05 | — | — | EP | disclosed |
| CN-115023446-A | Process for preparing catalyst and catalyst composition | 台塑工业美国公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-0723976-A2 | Dry prepolymerized catalyst for olefin polymerization, process for preparing the same and gas phase olefin polymerization process | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-31 | — | — | EP | disclosed |
| EP-0512741-B1 | Process for producing a propylene random copolymer | MITSUBISHI CHEM CORP (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0697419-A1 | Olefin polymerization catalyst and process for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-21 | — | — | EP | disclosed |
| EP-0692505-A2 | Process for procucing propylene block copolymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5449650-A | Catalyst components for polymerization of olefins and use thereof | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5434115-A | Process for producing olefin polymer | TOSOH CORPORATION (JP) | 1995-07-18 | — | — | US | disclosed |
| JP-H072935-A | CATALYST COMPONENT FOR PRODUCING POLYOLEFIN AND PRODUCTION OF POLYOLEFIN | SHOWA DENKO KK | 1995-01-06 | — | — | JP | disclosed |
| EP-0512741-A1 | Process for producing a propylene random copolymer | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-11 | — | — | EP | disclosed |