Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29556732 | 0.89 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL540483 | 0.89 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7937688 | 0.86 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9861299 | 0.79 | PNMT (0.38) | PNMTNPC1RAB9ADRD2DRD4 | |
| Fluorene SCHEMBL5087300 | 0.78 | MAOA (0.52) | PNMTNPC1RAB9ADRD3HTR2B | |
| Fluorene SCHEMBL28049914 | 0.76 | MAOA (0.50) | PNMTNPC1RAB9ADRD3HTR2B | |
| SCHEMBL30103334 | 0.73 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL524602 | 0.73 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL29546213 | 0.72 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4832744 | 0.72 | PNMT (0.42) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372478-B | Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof | 万华化学集团股份有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-113372478-A | Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof | 万华化学集团股份有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-113372478-B | Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof | 万华化学集团股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113372478-A | Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof | 万华化学集团股份有限公司 | 2021-09-10 | — | — | CN | disclosed |