SCHEMBL5405932

SCHEMBL5405932

[CH2]CCCN(CC)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 13/20 0.48
DNM1 Q05193 3/20 0.44
PLA2G1B P04054 1/20 0.42
PLA2G2A P14555 1/20 0.42
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
KDM5A P29375 1/20 0.37
KDM4C Q9H3R0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5398325 1.00 KCNH2 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL5387478 0.91 KCNH2 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL5390818 0.91 KCNH2 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL5265112 0.90 KCNH2 (0.40) KCNH2PLA2G1BPLA2G2AKDM5AKDM4C
SCHEMBL1405764 0.90 DNM1 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL4395765 0.90 DNM1 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL3251808 0.90 DNM1 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL4398450 0.90 DNM1 (0.48) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL21065771 0.88 KCNH2 (0.47) KCNH2DNM1PLA2G1BPLA2G2ATSHR
SCHEMBL3480698 0.87 DNM1 (0.43) KCNH2DNM1TSHRTHRBKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461375-B2 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling EVONIK RÖHM GMBH (DE) 2013-06-11 US disclosed
EP-1583733-B1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING EVONIK ROEHM GMBH (DE) 2013-04-24 EP disclosed
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP disclosed
US-7268251-B2 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US disclosed
US-20060211880-A1 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling ROEHM GMBH & CO. KG (DE) 2006-09-21 US disclosed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US disclosed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP disclosed
EP-1583733-A1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING Röhm GmbH & Co. KG (DE) 2005-10-12 EP disclosed
US-20040171868-A1 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2004-09-02 US disclosed
CN-1525953-A Method for producing (meth) acrylic acid esters �����ɷ� 2004-09-01 CN disclosed
US-20040158096-A1 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
WO-2004063140-A1 IMPROVED METHOD FOR THE CONTINUOUS PRODUCTION OF ALKYL(METH)ACRYLATES WITH MULTIPLE CATALYST RECYCLING Röhm GmbH & Co. KG (DE) 2004-07-29 WO disclosed
EP-1399408-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2004-03-24 EP disclosed
EP-1399409-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2004-03-24 EP disclosed
WO-2002100815-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed
WO-2002100814-A1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171868-A1 Method for producing (meth) acrylic acid esters ADH1A, ADH5, ADH1C KCNH2 4056/4885DNM1 1568/4885PLA2G1B 2587/4885
US-20060211880-A1 Method for the continuous production of alkyl(meth)acrylates with multiple catalyst recycling ADH5, ADH1A, ADH1C KCNH2 1869/4885DNM1 2066/4885PLA2G1B 2249/4885
US-20040158096-A1 Method for producing (meth)acrylic acid esters ADH1A, ADH5, ADH1C KCNH2 4099/4885DNM1 2335/4885PLA2G1B 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.