SCHEMBL5406368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5394163	0.93	CHRNB2 (0.59)	CHRNB2CHRNA4ALDH1A1HPGDFFAR1
	SCHEMBL5402292	0.90	PTPN1 (0.52)	CHRNB2CHRNA4ALDH1A1HPGDMCL1
	SCHEMBL5402458	0.90	ALDH1A1 (0.55)	CHRNB2CHRNA4ALDH1A1PPARGKDM4E
	SCHEMBL5409109	0.89	CHRNB2 (0.54)	CHRNB2CHRNA4ALDH1A1HPGDSMN1; SMN2
	SCHEMBL5403714	0.89	CHRNB2 (0.56)	CHRNB2CHRNA4ALDH1A1F12PPARG
	SCHEMBL5397438	0.89	CHRNB2 (0.50)	CHRNB2CHRNA4FFAR1AKR1B1PTPN1
	SCHEMBL5392409	0.89	ALDH1A1 (0.50)	ALDH1A1PPARGKDM4EHPGDSMN1; SMN2
	SCHEMBL5406923	0.89	CHRNB2 (0.58)	CHRNB2CHRNA4ALDH1A1PPARGHPGD
	SCHEMBL5418399	0.89	ALDH1A1 (0.57)	CHRNB2CHRNA4ALDH1A1PPARGKDM4E
	SCHEMBL5399793	0.89	ALDH1A1 (0.57)	CHRNB2CHRNA4ALDH1A1PPARGKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.