Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382277 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL3947293 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL5396416 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL5782533 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL5749185 | 0.71 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL436813 | 0.69 | ALDH1A1 (0.72) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL6218407 | 0.69 | MAPT (0.60) | ALDH1A1LMNAHTTL3MBTL1CYP1A2 | |
| SCHEMBL1572805 | 0.68 | MAPT (0.47) | ALDH1A1LMNAHTTL3MBTL1MEN1 | |
| SCHEMBL3947795 | 0.68 | POLB (0.38) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL8622568 | 0.68 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTL3MBTL1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007505867-A | — | — | 2007-03-15 | — | — | JP | claimed |
| EP-1664047-A1 | SUBSTITUTED INDOLIZINE 1,2,3,6,7,8 DERIVATIVES, FGFS INHIBITORS, A METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | Sanofi-Aventis (FR) | 2006-06-07 | — | — | EP | claimed |
| WO-2005028476-A1 | SUBSTITUTED INDOLIZINE 1,2,3,6,7,8 DERIVATIVES, FGFS INHIBITORS, A METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-AVENTIS (FR) | 2005-03-31 | — | — | WO | claimed |
| EP-1664047-A1 | SUBSTITUTED INDOLIZINE 1,2,3,6,7,8 DERIVATIVES, FGFS INHIBITORS, A METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | Sanofi-Aventis (FR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005028476-A1 | SUBSTITUTED INDOLIZINE 1,2,3,6,7,8 DERIVATIVES, FGFS INHIBITORS, A METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-AVENTIS (FR) | 2005-03-31 | — | — | WO | disclosed |