Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168266 | 0.73 | POLB (0.31) | ALDH1A1POLBRAB9A | |
| SCHEMBL9056337 | 0.70 | PGR (0.44) | ALDH1A1PGRHTTTDP1 | |
| SCHEMBL5406946 | 0.70 | — | — | |
| SCHEMBL5406940 | 0.70 | — | — | |
| SCHEMBL9527144 | 0.69 | KDM4E (0.50) | ALDH1A1CDK4CCNA2CCND1CDK2 | |
| SCHEMBL5397188 | 0.69 | PGR (0.43) | ALDH1A1PGRCDK4CCNA2CCND1 | |
| SCHEMBL4056890 | 0.68 | KDM4E (0.38) | ALDH1A1PGRHTTTP53 | |
| SCHEMBL7168725 | 0.67 | POLB (0.33) | ALDH1A1POLBRAB9A | |
| SCHEMBL6262202 | 0.66 | PGR (0.46) | ALDH1A1PGRPOLB | |
| SCHEMBL4830158 | 0.66 | PGR (0.50) | ALDH1A1PGRHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-7208142-B2 | Indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2007-04-24 | — | — | US | disclosed |
| EP-1466892-A1 | Novel indanylidene compounds | Symrise GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| EP-1341752-B1 | NOVEL INDANYLIDENE COMPOUNDS | SYMRISE GMBH & CO KG (DE) | 2004-08-04 | — | — | EP | disclosed |
| CN-1473146-A | Novel indanylidene compounds | ��������ķ������ | 2004-02-04 | — | — | CN | disclosed |
| EP-0823418-B1 | Indanylidene derivatives and their use as UV-absorbers | HAARMANN & REIMER GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-20020143203-A1 | Novel indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2002-10-03 | — | — | US | disclosed |
| US-6160094-A | aroA | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-6156956-A | Control of fruit ripening through genetic control of ACC synthase synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF AGRICULTURE (US) | 2000-12-05 | — | — | US | disclosed |
| US-6153175-A | Indanylidene compounds, a process for their preparation and their use as UV absorbers | HAARMANN & REIMER GMBH (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6008020-A | A POLYNUCLEOTIDE; THERAPY OF NERVOUS SYSTEM DISORDERS; HEMOSTATIC AND ANTITUMOR AGENT | HUMAN GENOME SCIENCES (US) | 1999-12-28 | — | — | US | disclosed |
| US-6004764-A | SCREENING METHODS FOR POTENTIAL THERAPEUTIC AGENTS WHICH REGULATE THE GROWTH OF M. TUBERCULOSIS; METHOD FOR IDENTIFYING GENES OF M. TUBERCULOSIS WHICH ARE REGULATED BY A SIGMA FACTOR OF M. TUBERCULOSIS | JOHNS HOPKINS UNIVERSITY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5965066-A | HIGH PROTECTION AGAINST BOTH UV-A AND UV-B RAYS AT LOW CONCENTRATIONS; RADIATION AND HEAT RESISTANCE; SUNSCREEN AGENTS; COSMETICS FOR SKIN AND HAIR | HAARMANN & REIMER GMBH (DE) | 1999-10-12 | — | — | US | disclosed |
| EP-0823418-A2 | Indanylidene derivatives, process for their preparation and their use as UV-absorbers | HAARMANN & REIMER GMBH (DE) | 1998-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | CUTA, NISCH, TYR | ALDH1A1 434/4885PGR 3055/4885POLB 2562/4885 |
| US-20020143203-A1 | Novel indanylidene compounds | CUTA, NISCH, ERCC4 | ALDH1A1 373/4885PGR 3741/4885POLB 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.