Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308840 | 0.86 | KDM4E (0.44) | QRFPRIGF1RGRM5MEN1KMT2A | |
| SCHEMBL13178587 | 0.81 | EGFR (0.39) | IMPDH2KMT2AABCG2 | |
| SCHEMBL3047670 | 0.80 | PLA2G7 (0.40) | MEN1KMT2A | |
| SCHEMBL13138552 | 0.79 | ABCG2 (0.54) | ABCG2 | |
| SCHEMBL16356879 | 0.78 | IGF1R (0.39) | IMPDH2IGF1RMEN1KMT2A | |
| SCHEMBL13138567 | 0.77 | BCL6 (0.39) | IMPDH2KMT2A | |
| SCHEMBL13138556 | 0.76 | FADS1 (0.43) | IMPDH2MEN1KMT2A | |
| SCHEMBL13138562 | 0.76 | ALDH1A1 (0.38) | IMPDH2KMT2A | |
| SCHEMBL3035542 | 0.75 | KDR (0.43) | MEN1KMT2AABCG2 | |
| SCHEMBL16671997 | 0.73 | EGFR (0.35) | IMPDH2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |