Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.33 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138556 | 0.85 | FADS1 (0.43) | EGFRBACE1IMPDH2ALDH1A1LMNA | |
| SCHEMBL13138538 | 0.85 | KDR (0.41) | EGFRCLK1LCKKDRTTBK1 | |
| SCHEMBL13138552 | 0.82 | ABCG2 (0.54) | EGFRABCG2CLK1KDRLMNA | |
| SCHEMBL13138562 | 0.80 | ALDH1A1 (0.38) | BACE1IMPDH2ALDH1A1CYP1B1 | |
| SCHEMBL13178587 | 0.78 | EGFR (0.39) | EGFRABCG2IMPDH2ALDH1A1 | |
| SCHEMBL5408787 | 0.73 | IMPDH2 (0.40) | ABCG2IMPDH2 | |
| SCHEMBL16356879 | 0.72 | IGF1R (0.39) | KDRCDK4CDK2IMPDH2ALDH1A1 | |
| SCHEMBL3047670 | 0.72 | PLA2G7 (0.40) | — | |
| SCHEMBL13138567 | 0.71 | BCL6 (0.39) | EGFRKDRIMPDH2ALDH1A1 | |
| SCHEMBL13138531 | 0.70 | FADS1 (0.51) | EGFRKDRBACE1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018209-B2 | Compounds and methods for the treatment of viruses and cancer | YALE UNIVERSITY (US) | 2015-04-28 | — | — | US | disclosed |