SCHEMBL5408967

SCHEMBL5408967

CC(=O)OC1[C]2CC3CC(C2)CC1C3

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.34
CHRM2 P08172 6/20 0.32
CHRM1 P11229 4/20 0.32
CHRM4 P08173 3/20 0.32
CHRM3 P20309 3/20 0.32
CHRM5 P08912 2/20 0.32
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16593662 0.72
SCHEMBL11479712 0.71 POLB (0.39) POLBTSHRCHRM2CHRM1CHRM4
SCHEMBL3197215 0.69 NLRP3 (0.33)
SCHEMBL3753073 0.69 HSD11B1 (0.50) TSHRCHRM2CHRM1CHRM4CHRM3
SCHEMBL706994 0.65 CHRNB2 (0.39) POLBMEN1KMT2A
SCHEMBL384602 0.63 HSD11B1 (0.35) TSHR
SCHEMBL25090572 0.61 POLB (0.42) POLBTSHRCHRM2CHRM1CHRM4
SCHEMBL18007757 0.61
SCHEMBL1401345 0.60 CHRM2 (0.38) POLBTSHRCHRM2CHRM1CHRM4
SCHEMBL7064281 0.60 HSD11B1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7192684-B2 Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-03-20 US disclosed
US-20040067436-A1 Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-04-08 US disclosed