SCHEMBL384602

SCHEMBL384602

O=C(O)C1[C]2CC3CC(C2)CC1C3

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.35
EPHX2 P34913 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064281 0.90 HSD11B1 (0.31) HSD11B1
SCHEMBL706994 0.75 CHRNB2 (0.39) EPHX2
SCHEMBL15840889 0.70 HSD11B1 (0.42) HSD11B1EPHX2TSHR
SCHEMBL8781862 0.69 EPHX2 (0.36) HSD11B1EPHX2
SCHEMBL76842 0.65 CYP2C9 (0.41)
SCHEMBL2707599 0.64 CYP2C9 (0.32)
SCHEMBL7978669 0.64 GRM5 (0.34) HSD11B1TSHR
SCHEMBL5408967 0.63 POLB (0.35) TSHR
SCHEMBL7794306 0.62 GAA (0.32)
SCHEMBL16698251 0.62 HSD11B1 (0.48) HSD11B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112239623-B Polymer for display device 罗门哈斯电子材料有限责任公司 2022-10-04 CN claimed
CN-112239623-A Polymer for display device 罗门哈斯电子材料有限责任公司 2021-01-19 CN claimed
EP-2633099-B1 AQUEOUS COMPOSITION FOR PRETREATING A METAL SURFACE BEFORE APPLYING ANOTHER COATING OR FOR TREATING SAID SURFACE CHEMETALL GMBH (DE) 2019-07-03 EP claimed
US-9481935-B2 Aqueous composition for pretreating a metal surface before applying another coating or for treating said surface CHEMETALL GMBH (DE) 2016-11-01 US claimed
EP-2280970-B1 IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS HOFFMANN LA ROCHE (CH) 2014-01-08 EP claimed
US-20130295292-A1 AQUEOUS COMPOSITION FOR PRETREATING A METAL SURFACE BEFORE APPLYING ANOTHER COATING OR FOR TREATING SAID SURFACE CHEMETALL GMBH (DE) 2013-11-07 US claimed
US-8182865-B2 Process for producing a repair coating on a coated metallic surface CHEMETALL GMBH (DE) 2012-05-22 US claimed
US-8124636-B2 Imidazolidinone derivatives as 11B-HSD1 inhibitors HOFFMANN-LA ROCHE INC. (US) 2012-02-28 US claimed
EP-2280970-A1 IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS F. Hoffmann-La Roche AG (CH) 2011-02-09 EP claimed
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2010-12-16 US claimed
WO-2009132986-A1 IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2009-11-05 WO claimed
US-20090275573-A1 Imidazolidinone Derivatives as 11B-HSD1 Inhibitors HOFFMANN-LA ROCHE, INC. 2009-11-05 US claimed
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors ASTRAZENECA AB (SE) 2008-04-24 US claimed
EP-1833806-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS AstraZeneca AB (SE) 2007-09-19 EP claimed
WO-2006064189-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2006-06-22 WO claimed
EP-1004568-B1 Novel ester compounds, polymers, resist compositions and patterning process SHINETSU CHEMICAL CO (JP) 2006-01-25 EP claimed
US-6596463-B2 Photosensitivity, resolution, chemical resistance SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2003-07-22 US claimed
US-6312867-B1 Ester compounds, polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-06 US claimed
CN-118240154-A Curable composition and film made therefrom 罗门哈斯电子材料韩国有限公司 2024-06-25 CN disclosed
EP-0820444-A1 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS SANOFI (FR) 1998-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS DGAT1, DGAT2, GPR119 HSD11B1 117/4885EPHX2 2036/4885TSHR 1451/4885
US-20090275573-A1 Imidazolidinone Derivatives as 11B-HSD1 Inhibitors HSD11B1, HSD17B1, HSD17B11 HSD11B1 1/4885EPHX2 2366/4885TSHR 1734/4885
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors DGAT1, DGAT2, GPR119 HSD11B1 126/4885EPHX2 2517/4885TSHR 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.