Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163237 | 0.88 | RAB9A (0.40) | HSD17B10HPGDMEN1KMT2ARAB9A | |
| SCHEMBL5161584 | 0.86 | HSD17B10 (0.39) | EPHX1HSD17B10HPGDKMT2ANPC1 | |
| SCHEMBL5163678 | 0.78 | ALOX5AP (0.36) | HSD17B10LMNANPSR1MEN1KMT2A | |
| SCHEMBL5160339 | 0.78 | HCRTR2 (0.32) | KMT2ASMN1; SMN2 | |
| SCHEMBL5161515 | 0.75 | EPHX1 (0.39) | EPHX1HSD17B10LMNANPSR1HPGD | |
| SCHEMBL14457242 | 0.73 | HSD17B10 (0.50) | EPHX1HSD17B10LMNANPSR1HPGD | |
| SCHEMBL925960 | 0.73 | HSD17B10 (0.50) | EPHX1HSD17B10LMNANPSR1HPGD | |
| SCHEMBL9977242 | 0.73 | HSD17B10 (0.50) | EPHX1HSD17B10LMNANPSR1HPGD | |
| SCHEMBL5409095 | 0.73 | USP30 (0.38) | EPHX1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL7527261 | 0.72 | TSHR (0.45) | RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | EPHX1 3451/4885HSD17B10 3097/4885LMNA 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.