Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420858 | 0.81 | TSHR (0.39) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL5419195 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL5414937 | 0.79 | TSHR (0.38) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL5420384 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL11668297 | 0.77 | SLC6A4 (0.42) | OPRM1OGFRL1LMNA | |
| SCHEMBL5427095 | 0.76 | TSHR (0.44) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL6530065 | 0.76 | CYP1A2 (0.39) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL5424845 | 0.75 | CYP1A2 (0.39) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL11864568 | 0.74 | OPRM1 (0.52) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 | |
| SCHEMBL5416808 | 0.74 | S1PR4 (0.36) | ALDH1A1TSHRNFKB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | WYETH (US) | 2007-11-29 | — | — | US | claimed |
| WO-2005016932-A1 | PYRANOBENZOTHIOPHENE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2005-02-24 | — | — | WO | claimed |
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | WYETH (US) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | LIPC, HAVCR2, GTF3C2 | ALDH1A1 767/4885TSHR 1214/4885NFKB1 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.