Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420858 | 0.77 | TSHR (0.39) | OPRM1OGFRL1TSHRPTGS1GAA | |
| SCHEMBL5424845 | 0.75 | CYP1A2 (0.39) | S1PR4OPRM1OGFRL1TSHRPTGS1 | |
| SCHEMBL5415334 | 0.74 | ALDH1A1 (0.36) | OPRM1OGFRL1TSHRPTGS1LMNA | |
| SCHEMBL5416372 | 0.73 | CYP1A2 (0.38) | S1PR4S1PR5PTGER4OPRM1OGFRL1 | |
| SCHEMBL5419195 | 0.73 | ALDH1A1 (0.53) | OPRM1OGFRL1TSHRPTGS1LMNA | |
| SCHEMBL5414937 | 0.72 | TSHR (0.38) | OPRM1OGFRL1TSHRPTGS1AKR1B1 | |
| SCHEMBL6530065 | 0.72 | CYP1A2 (0.39) | OPRM1OGFRL1TSHRPTGS1HTT | |
| SCHEMBL5420384 | 0.71 | ALDH1A1 (0.46) | OPRM1OGFRL1TSHRPTGS1LMNA | |
| SCHEMBL5427095 | 0.70 | TSHR (0.44) | OPRM1OGFRL1TSHRPTGS1ALDH1A1 | |
| SCHEMBL11674036 | 0.64 | LMNA (0.38) | OPRM1OGFRL1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021451-A | P-(3,4-DIHYDRO-1-METHYL-1H-(1)BENZOTHIENO(2,3-C)PYRAN-1-YL)PHENYL) -ACETIC ACID | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-03 | — | — | US | claimed |
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | WYETH (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2005016932-A1 | PYRANOBENZOTHIOPHENE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2005-02-24 | — | — | WO | disclosed |
| US-4036842-A | FRIEDEL CRAFTS CATALYST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276030-A1 | Pyranobenzothiophene derivatives to treat infection with hepatitis c virus | LIPC, HAVCR2, GTF3C2 | S1PR4 3641/4885S1PR5 3752/4885PTGER4 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.