Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775560 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8027968 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL30781559 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5292911 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL22506727 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL2108243 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL29475787 | 0.86 | ADRB2 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL7889777 | 0.86 | ADRB2 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL22497578 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL28459278 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329908-B2 | Dual action antibiotics | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2012-12-11 | — | — | US | disclosed |
| EP-2296651-B1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES FOR TREATING BACTERIAL INTESTINAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-8124623-B2 | 5-hydroxymethyl-oxazolidin-2-one-derivatives and their uses as antibacterials | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-02-28 | — | — | US | disclosed |
| EP-2086968-B1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-08 | — | — | EP | disclosed |
| CN-101381365-B | Dual action antibiotics | MORPHOCHEM AG KOMB CHEMIE | 2011-07-06 | — | — | CN | disclosed |
| US-20110059946-A1 | DUAL ACTION ANTIBIOTICS | MORPHOCHEM AKTIENGESELLSCHAFT FUER KOMBINATORISCHE CHEMIE (DE) | 2011-03-10 | — | — | US | disclosed |
| US-7820823-B2 | Dual action antibiotics | Morphochem Aktiengesellschaft Fur Kominatorische Chemi (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20090247578-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-10-01 | — | — | US | disclosed |
| EP-1432705-B1 | DUAL ACTION ANTIBIOTICS | MORPHOCHEM AG KOMB CHEMIE (DE) | 2007-08-08 | — | — | EP | disclosed |
| CN-1630655-A | Dual action antibiotics | MORPHOCHEM AG FUER KOM (DE) | 2005-06-22 | — | — | CN | disclosed |
| US-20050096343-A1 | Dual action antibiotics | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247578-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS | OGFOD1, OXGR1, ODC1 | ALDH1A1 1227/4885KDM4E 1365/4885LMNA 4824/4885 |
| US-20050096343-A1 | Dual action antibiotics | SLC11A2, MRPL21, MAP2K5 | ALDH1A1 2592/4885KDM4E 4461/4885LMNA 3271/4885 |
| US-20110059946-A1 | DUAL ACTION ANTIBIOTICS | SLC11A2, MRPL21, MAP2K5 | ALDH1A1 2994/4885KDM4E 4589/4885LMNA 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.