Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25491606 | 1.00 | KLK7 (0.59) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL4370045 | 0.94 | KLK5 (0.65) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL14456732 | 0.92 | KLK7 (0.52) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL5623452 | 0.92 | KLK7 (0.52) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL16286010 | 0.90 | CACNA1B (0.59) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL20481004 | 0.90 | CACNA1B (0.59) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL20144655 | 0.90 | CACNA1B (0.59) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL9943561 | 0.89 | KLK5 (0.65) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL9943562 | 0.89 | KLK5 (0.65) | KLK7KLK5CACNA1BPPARASYK | |
| SCHEMBL12585497 | 0.89 | KLK5 (0.65) | KLK7KLK5CACNA1BPPARASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083291-A1 | DERIVATIVE OF ASPARTIC ACID AND USE THEREOF IN TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS | 深圳利沃生物医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |
| US-20070249670-A1 | Glycogen Phosphorylase Inhibitor Compounds and Pharmaceutical Compositions Thereof | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249670-A1 | Glycogen Phosphorylase Inhibitor Compounds and Pharmaceutical Compositions Thereof | PYGM, PYGL, GYS1 | KLK7 3432/4885KLK5 1667/4885CACNA1B 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.