SCHEMBL5422992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5423126	0.91	KDM4E (0.68)	KDM4EALDH1A1TDP1CYP19A1GSK3B
	SCHEMBL5426580	0.86	KDM4E (0.67)	KDM4EALDH1A1TDP1CYP19A1GSK3B
	SCHEMBL9561573	0.85	ALDH1A1 (0.69)	KDM4EALDH1A1POLBNPC1RAB9A
	SCHEMBL16109895	0.84	ALDH1A1 (0.67)	KDM4EALDH1A1TDP1NPC1RAB9A
	SCHEMBL12588233	0.84	KDM4E (0.76)	KDM4EALDH1A1TDP1CYP19A1GSK3B
	SCHEMBL5426967	0.84	KDM4E (0.76)	KDM4EALDH1A1TDP1CYP19A1HDAC1
	SCHEMBL18116704	0.82	KDM4E (0.74)	KDM4EALDH1A1TDP1CYP19A1HDAC1
	SCHEMBL16111493	0.82	ALDH1A1 (0.63)	KDM4EALDH1A1HDAC6NPC1RAB9A
	SCHEMBL5423478	0.81	KDM4E (0.72)	KDM4EALDH1A1TDP1CYP19A1HDAC1
	SCHEMBL12143427	0.81	KDM4E (0.72)	KDM4EALDH1A1TDP1CYP19A1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.