Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13116578 | 0.91 | HPGD (0.57) | ALDH1A1KDM4EKMT2AHPGDNPC1 | |
| SCHEMBL16109895 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AHPGDNPC1 | |
| SCHEMBL5422992 | 0.85 | KDM4E (0.74) | ALDH1A1KDM4EKMT2AHPGDNPC1 | |
| SCHEMBL9561214 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AHPGDHPGDS | |
| SCHEMBL14959680 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AHPGDHPGDS | |
| SCHEMBL8824851 | 0.82 | L3MBTL1 (0.61) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL2428778 | 0.82 | HCAR3 (0.63) | ALDH1A1KDM4EHPGDTP53L3MBTL1 | |
| SCHEMBL16111493 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL7660982 | 0.81 | POLB (0.56) | ALDH1A1KDM4EKMT2AHPGDNPC1 | |
| SCHEMBL8869449 | 0.81 | P4HTM (0.48) | ALDH1A1KDM4EKMT2AHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |