SCHEMBL5426580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5422992	0.86	KDM4E (0.74)	KDM4ETDP1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL13450252	0.86	SMN1; SMN2 (0.52)	KDM4EALDH1A1SMN1; SMN2HPGDNPC1
	SCHEMBL5426967	0.85	KDM4E (0.76)	KDM4ETDP1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL18116704	0.83	KDM4E (0.74)	KDM4ETDP1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL5423478	0.83	KDM4E (0.72)	KDM4ETDP1ALDH1A1CYP19A1POLB
	SCHEMBL5438583	0.82	KDM4E (0.63)	KDM4ETDP1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL5423126	0.80	KDM4E (0.68)	KDM4ETDP1ALDH1A1CYP19A1SMN1; SMN2
	SCHEMBL12588233	0.79	KDM4E (0.76)	KDM4ETDP1ALDH1A1CYP19A1GSK3B
	SCHEMBL1543075	0.79	MAPK14 (0.48)	KDM4EALDH1A1SMN1; SMN2HPGDNPC1
	SCHEMBL4354408	0.77	NAAA (0.67)	TDP1ALDH1A1SMN1; SMN2HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.