Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 5/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423338 | 0.86 | KDM4E (0.51) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL14500666 | 0.84 | ALDH1A1 (0.49) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL14500331 | 0.81 | KDM4E (0.50) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5419258 | 0.80 | KDM4E (0.49) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL5419204 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL7486918 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL8809305 | 0.76 | KDM4E (0.58) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL7485064 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL7488125 | 0.74 | TP53 (0.44) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL15968765 | 0.74 | CTNNB1 (0.57) | ALDH1A1MAPTHPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20030158177-A1 | Treating or preventing obesity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158177-A1 | Treating or preventing obesity | MCHR1, MC1R, NPY1R | PDK1 2915/4885PDK2 1833/4885PDK3 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.