SCHEMBL542369

SCHEMBL542369

[CH]=CCCCCCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.52
MAOA P21397 1/20 0.50
MAPT P10636 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
MAOB P27338 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128969 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL3939372 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL17558060 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1144005 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL8735183 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1144123 0.98 MAOA (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL542843 0.91 SIGMAR1 (0.48) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL9825321 0.82 SIGMAR1 (0.56) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL542482 0.81 ALDH1A1 (0.48) SIGMAR1MAOAMAOB
SCHEMBL6546948 0.81 SIGMAR1 (0.71) SIGMAR1MAOAMAPTRXFP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586418-A1 SUBSTITUTED TRIAZOLINONES BAYER AG (DE) 1994-03-16 EP claimed
US-5276008-A Herbicides and plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1994-01-04 US claimed
WO-1992020663-A1 SUBSTITUTED TRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1992-11-26 WO claimed
EP-0502307-A2 Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones BAYER AG (DE) 1992-09-09 EP claimed
US-20230012337-A1 POLYESTERS CLARIANT INTERNATIONAL LTD. (CH) 2023-01-12 US disclosed
WO-2021118814-A1 A DETERGENT COMPOSITION COMPRISING A POLYMER THE PROCTER & GAMBLE COMPANY (US) 2021-06-17 WO disclosed
WO-2021116049-A1 POLYESTERS CLARIANT INTERNATIONAL LTD (CH) 2021-06-17 WO disclosed
EP-3835396-A1 A DETERGENT COMPOSITION COMPRISING A POLYMER The Procter & Gamble Company (US) 2021-06-16 EP disclosed
US-20210171874-A1 DETERGENT COMPOSITION COMPRISING A POLYMER THE PROCTER AND GAMBLE COMPANY 2021-06-10 US disclosed
EP-2808359-B1 OLEFIN BASED POLYMER-COMBINED ORGANIC-INORGANIC COMPOSITE AND COMPOSITION FOR FORMING SAME NIPPON SODA CO (JP) 2018-04-04 EP disclosed
EP-2090600-B1 ORGANIC-INORGANIC COMPOSITE BODY NIPPON SODA CO (JP) 2018-03-07 EP disclosed
US-9790400-B2 Organic-inorganic complex, and forming composition thereof NIPPON SODA CO., LTD. (JP) 2017-10-17 US disclosed
US-4427563-A LUBRICATING OIL ADDITIVES ATLANTIC RICHFIELD COMPANY (US) 1984-01-24 US disclosed
US-4306985-A PHOTOSTABILITY ATLANTIC RICHFIELD COMPANY (US) 1981-12-22 US disclosed
EP-0040516-A1 Stabilization of hydrocracked oils with certain dihydroxy diphenyl components ATLANTIC RICHFIELD COMPANY (US) 1981-11-25 EP disclosed
US-3987087-A ANTI-ULCER, NASAL PATENCY, WOUND HEALING, LABOR INDUCEMENT THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3983158-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-28 US disclosed
US-3983157-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-28 US disclosed
US-3980694-A ANTIULCER, ANTIAGGLOMERANTS, INCREASE OF NASAL PATENCY, LABOR INDUCEMENT, WOUND HEALINGPROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-14 US disclosed
US-3931289-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US disclosed