SCHEMBL8735183

SCHEMBL8735183

[CH]=CCCCCCCCCCCCCCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.52
MAOA P21397 1/20 0.50
MAPT P10636 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
MAOB P27338 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128969 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL3939372 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL542369 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL17558060 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1144005 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1144123 0.98 MAOA (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL542843 0.91 SIGMAR1 (0.48) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL9825321 0.82 SIGMAR1 (0.56) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL542482 0.81 ALDH1A1 (0.48) SIGMAR1MAOAMAOB
SCHEMBL6546948 0.81 SIGMAR1 (0.71) SIGMAR1MAOAMAPTRXFP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP claimed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US claimed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP claimed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US claimed
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US disclosed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US disclosed
EP-0697449-A2 Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1996-02-21 EP disclosed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP disclosed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US disclosed