Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403188 | 0.91 | TSHR (0.62) | TSHRCYP3A4MAPK1TDP1HSD17B10 | |
| SCHEMBL107751 | 0.91 | TSHR (0.62) | TSHRCYP3A4MAPK1TDP1HSD17B10 | |
| SCHEMBL21995301 | 0.76 | TSHR (0.60) | TSHRCYP3A4MAPK1TDP1HSD17B10 | |
| SCHEMBL3789153 | 0.75 | CYP3A4 (0.52) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL364003 | 0.74 | HSD17B10 (0.52) | HSD17B10NOTUMKMOPDK2 | |
| SCHEMBL10662295 | 0.74 | HSD17B10 (0.50) | TSHRCYP3A4MAPK1TDP1HSD17B10 | |
| SCHEMBL31740316 | 0.74 | TSHR (0.58) | TSHRCYP3A4MAPK1TDP1HSD17B10 | |
| SCHEMBL27999682 | 0.74 | HSD11B1 (0.42) | TSHRTDP1KDM4EHSD11B1CYP19A1 | |
| SCHEMBL30026190 | 0.74 | HSD17B10 (0.52) | HSD17B10NOTUMKMOPDK2 | |
| SCHEMBL16211981 | 0.74 | TSHR (0.58) | TSHRCYP3A4MAPK1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | ISHIHARA SANGYO KAISHA LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| EP-1681924-A1 | BIPHENYL DERIVATIVE OR ITS SALT, AND PESTICIDE CONTAINING IT AS AN ACTIVE INGREDIENT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044007-A1 | BIPHENYL DERIVATIVE OR ITS SALT, AND PESTICIDE CONTAINING IT AS AN ACTIVE INGREDIENT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | DDT, HCN1, HCN2 | TSHR 611/4885CYP3A4 2206/4885MAPK1 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.