SCHEMBL542833

SCHEMBL542833

O=C(O)c1cc(F)c(C(=O)O)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
MAPK1 P28482 2/20 0.50
TP53 P04637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CA3 P07451 1/20 0.50
MAPT P10636 1/20 0.50
SELL P14151 1/20 0.50
HPGD P15428 1/20 0.50
SELP P16109 1/20 0.50
FUT4 P22083 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL791574 0.84 TTR (0.54) LMNACA12CA1CA2CA7
SCHEMBL23764727 0.83 LMNA (0.44) LMNACA12CA1CA2CA7
SCHEMBL21957160 0.83 CA5A (0.44) LMNACA12CA1CA2CA7
SCHEMBL5053787 0.83 LMNA (0.44) LMNACA12CA1CA2CA7
SCHEMBL28888036 0.81 AKR1C2 (0.45) LMNACA12CA1CA2CA7
SCHEMBL14213195 0.81 TTR (0.55) LMNACA12CA1CA2CA7
SCHEMBL288979 0.81 CES2 (0.46) LMNACA1CA2KDM4EHSD17B10
SCHEMBL221480 0.81 CES2 (0.67) LMNACA12CA1CA2CA7
SCHEMBL17177745 0.79 AKR1C2 (0.44) LMNACA12CA1CA2CA7
SCHEMBL4365047 0.79 CA12 (0.64) LMNACA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150658-B Corrosion-resistant weather-resistant flame-retardant polyester resin for powder coating 山东尚核电力科技有限公司 2022-10-25 CN claimed
CN-112961334-B Polyester resin for corrosion-resistant weather-resistant high-storage-performance powder coating 山东尚核电力科技有限公司 2022-08-12 CN claimed
CN-113150658-A Corrosion-resistant weather-resistant flame-retardant polyester resin for powder coating 山东尚核电力科技有限公司 2021-07-23 CN claimed
CN-112961334-A Polyester resin for corrosion-resistant weather-resistant high-storage-performance powder coating 山东尚核电力科技有限公司 2021-06-15 CN claimed
CN-113150658-B Corrosion-resistant weather-resistant flame-retardant polyester resin for powder coating 山东尚核电力科技有限公司 2022-10-25 CN disclosed
CN-112961334-B Polyester resin for corrosion-resistant weather-resistant high-storage-performance powder coating 山东尚核电力科技有限公司 2022-08-12 CN disclosed
WO-2021161109-A1 PREPARATION OF A P2X3 ANTAGONIST BELLUS HEALTH COUGH INC. (CA) 2021-08-19 WO disclosed
CN-113150658-A Corrosion-resistant weather-resistant flame-retardant polyester resin for powder coating 山东尚核电力科技有限公司 2021-07-23 CN disclosed
CN-112961334-A Polyester resin for corrosion-resistant weather-resistant high-storage-performance powder coating 山东尚核电力科技有限公司 2021-06-15 CN disclosed
CN-110776928-A Liquid crystal resin matrix for high-frequency printed circuit board and preparation method thereof 东华大学 2020-02-11 CN disclosed
US-9458354-B2 Polyurethane dispersions and methods of making and using same Resinate Technologies, Inc. (US) 2016-10-04 US disclosed
US-20120259061-A1 Polyurethane Dispersions and Methods of Making and Using Same RESINATE MATERIALS GROUP, INC. 2012-10-11 US disclosed
CN-100442091-C Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2008-12-10 CN disclosed
EP-1978008-A1 METHOD FOR PRODUCING HALOGEN-SUBSTITUTED BENZENEDIMETHANOL Sumitomo Chemical Company, Limited (JP) 2008-10-08 EP disclosed
CN-1759333-A Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2006-04-12 CN disclosed
CN-1759334-A Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2006-04-12 CN disclosed
EP-0741122-B1 Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids CLARIANT GMBH (DE) 1999-08-25 EP disclosed
US-5739388-A Process for the preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
CN-1138023-A Process for preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids HOECHST AG (DE) 1996-12-18 CN disclosed
EP-0741122-A1 Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-06 EP disclosed