Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227770 | 0.96 | PPARG (0.45) | PPARGPPARACYP2C9KCNH2TP53 | |
| SCHEMBL5264766 | 0.94 | PPARG (0.47) | PPARGPPARATP53MAPTPPARD | |
| SCHEMBL5227577 | 0.93 | PPARA (0.50) | PPARGPPARACYP2C9KCNH2TP53 | |
| SCHEMBL5263899 | 0.93 | FFAR1 (0.49) | PPARGPPARATP53MAPTFFAR1 | |
| SCHEMBL5434591 | 0.90 | PPARG (0.48) | PPARGPPARATP53MAPT | |
| SCHEMBL5232315 | 0.89 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5228225 | 0.89 | PPARA (0.51) | PPARGPPARACYP2C9KCNH2TP53 | |
| SCHEMBL5441640 | 0.89 | MAPT (0.48) | PPARGPPARACYP2C9KCNH2TP53 | |
| SCHEMBL5432331 | 0.89 | FFAR1 (0.51) | PPARGPPARATP53MAPTFFAR1 | |
| SCHEMBL5231626 | 0.88 | PPARG (0.49) | PPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254882-A1 | Sulfamide Derivatives and Pharmaceutical Composition for Upregulation of Lipid Metabolism Comprising Same | CRYSTAL GENOMICS, INC. (KR) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254882-A1 | Sulfamide Derivatives and Pharmaceutical Composition for Upregulation of Lipid Metabolism Comprising Same | SULT2A1, SPTLC2, SGMS2 | PPARG 399/4885PPARA 190/4885CYP2C9 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.