Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777551 | 0.74 | GBA1 (0.46) | GBA1GAATP53MGLLFAAH | |
| SCHEMBL26634742 | 0.74 | MGLL (0.46) | GBA1GAATP53MGLLFAAH | |
| SCHEMBL14477951 | 0.74 | ALDH1A1 (0.47) | GBA1GAAMAPTALDH1A1THRB | |
| SCHEMBL14478052 | 0.73 | MEN1 (0.49) | GBA1GAATP53ALDH1A1POLB | |
| SCHEMBL11472539 | 0.72 | PER2 (0.40) | PER2SIGMAR1 | |
| SCHEMBL11488636 | 0.72 | PER2 (0.38) | PER2SIGMAR1 | |
| SCHEMBL24688924 | 0.71 | MGLL (0.44) | MGLLFAAHMAPTCYP19A1PTGS1 | |
| SCHEMBL4635213 | 0.70 | CHRM2 (0.45) | GBA1GAATP53MGLLFAAH | |
| SCHEMBL25149470 | 0.70 | GAA (0.38) | GBA1GAATP53ALDH1A1CYP19A1 | |
| SCHEMBL4588206 | 0.69 | PTGER4 (0.46) | GBA1GAATP53MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855546-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177513-A1 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| EP-1809344-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | Johnson and Johnson Vision Care, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006039467-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | disclosed |