Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 6/20 | 0.61 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.61 |
| ▸ | FPR3 | P25089 | 1/20 | 0.61 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Reminertant SCHEMBL1650932 | 0.76 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL29376784 | 0.76 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL19026903 | 0.70 | NTSR1 (0.87) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9078221 | 0.67 | NTSR1 (0.75) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL7556717 | 0.66 | NTSR1 (0.81) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8395699 | 0.66 | NTSR1 (0.66) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8590399 | 0.66 | NTSR1 (0.80) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL17114634 | 0.63 | NTSR1 (0.75) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9082598 | 0.62 | NTSR1 (0.43) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9153323 | 0.62 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413970-A2 | New therapeutic approaches for treating neuroinflammatory conditions | Pharnext (FR) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115741-A2 | NEW THERAPEUTIC APPROACHES FOR TREATING NEUROINFLAMMATORY CONDITIONS | PHARNEXT (FR) | 2010-10-14 | — | — | WO | disclosed |