Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349422 | 0.84 | HDAC8 (0.44) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL781852 | 0.84 | HDAC8 (0.44) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL29846591 | 0.82 | ALDH1A1 (0.48) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL18302082 | 0.82 | HDAC8 (0.47) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL26018 | 0.82 | TDP1 (0.54) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL309484 | 0.82 | ALDH1A1 (0.48) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL28723791 | 0.82 | HDAC8 (0.42) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL16952172 | 0.82 | HDAC8 (0.47) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL30277113 | 0.82 | TDP1 (0.54) | HDAC8HDAC4HDAC2KIF11ACHE | |
| SCHEMBL7545113 | 0.80 | NFE2L2 (0.53) | HDAC8HDAC4HDAC2NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176220-A | Catalyst for olefin polymerization and process for producing olefin polymer | 国立大学法人东京大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20070189058-A1 | Molecular system and method for reversibly switching the same between four states | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2007-08-16 | — | — | US | disclosed |
| US-20070112103-A1 | Molecular system and method for reversibly switching the same | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2007-05-17 | — | — | US | disclosed |