Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433181 | 0.84 | HDAC8 (0.45) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL349422 | 0.82 | HDAC8 (0.44) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL30277113 | 0.80 | TDP1 (0.54) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL16952172 | 0.80 | HDAC8 (0.47) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL26018 | 0.80 | TDP1 (0.54) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL29846591 | 0.80 | ALDH1A1 (0.48) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL309484 | 0.80 | ALDH1A1 (0.48) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL18302082 | 0.80 | HDAC8 (0.47) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL28723791 | 0.80 | HDAC8 (0.42) | HDAC8HDAC4HDAC2ACHEKIF11 | |
| SCHEMBL7545113 | 0.78 | NFE2L2 (0.53) | HDAC8HDAC4HDAC2NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614358-B2 | Process for preparing 2-methyl-3-(4-tert-butylphenyl)propanal with high para-isomer purity | BASF SE (DE) | 2013-12-24 | — | — | US | disclosed |
| US-20120071696-A1 | PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071696-A1 | PROCESS FOR PREPARING 2-METHYL-3-(4-TERT-BUTYLPHENYL)PROPANAL WITH HIGH PARA-ISOMER PURITY | HPD, PAH, PTMA | HDAC8 4112/4885HDAC4 3435/4885HDAC2 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.