SCHEMBL5433205

SCHEMBL5433205

C=CC(=O)OC(C=C)OC(=O)c1ccccc1C=O

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
THRB P10828 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SRC P12931 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10427916 0.82 ALDH1A1 (0.42) CYP3A4THRBKMT2ATDP1ALDH1A1
SCHEMBL7200118 0.79 KDM4E (0.38) CYP3A4THRBMEN1KMT2ATDP1
SCHEMBL890322 0.77 TSHR (0.49) THRBMEN1LMNAKMT2ATDP1
SCHEMBL7200123 0.75 KDM4E (0.40) CYP3A4THRBMEN1KMT2ATDP1
SCHEMBL14302947 0.75 CYP3A4 (0.36) CYP3A4THRBPTGDR2ALDH1A1TSHR
SCHEMBL6796993 0.73 TSHR (0.56) THRBMEN1LMNABLMKMT2A
SCHEMBL2222781 0.73 NPC1 (0.51) THRBMEN1LMNABLMKMT2A
SCHEMBL14302895 0.72 AKT1 (0.48) CYP3A4THRBMEN1LMNABLM
SCHEMBL277923 0.72 TSHR (0.39) CYP3A4LMNAALDH1A1TSHRHSD17B10
SCHEMBL1866176 0.69 TSHR (0.43) CYP3A4THRBLMNAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070112094-A1 Printing ink SERICOL LIMITED (GB) 2007-05-17 US claimed
JP-2007501289-A 2007-01-25 JP claimed
EP-1660598-A2 A PRINTING INK SERICOL LIMITED (GB) 2006-05-31 EP claimed
WO-2005012448-A2 A PRINTING INK SERICOL LIMITED (GB) 2005-02-10 WO claimed