Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427469 | 0.89 | MEN1 (0.49) | MEN1KMT2AHTR6KDM4EFBP1 | |
| SCHEMBL6765180 | 0.85 | LMNA (0.65) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL14687940 | 0.81 | MEN1 (0.47) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL4334870 | 0.80 | HTR6 (0.65) | MEN1KMT2AHTR6 | |
| SCHEMBL1156081 | 0.80 | KMT2A (0.56) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL16502710 | 0.79 | MEN1 (0.57) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL4794075 | 0.79 | KMT2A (0.55) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL9581555 | 0.79 | HTR6 (0.53) | MEN1KMT2AHTR6 | |
| SCHEMBL19737423 | 0.78 | HTR6 (0.59) | MEN1KMT2APLK1LMNASMN1; SMN2 | |
| SCHEMBL1355305 | 0.78 | HPGD (0.53) | LMNAAKR1C3AKR1C1HTR6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015813-A1 | Treatment of protein folding disorders | HSPA5, TTR, TUFM | MEN1 4065/4885KMT2A 3723/4885PLK1 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.