SCHEMBL543971

SCHEMBL543971

CC1(C(=O)O)OC1C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
LMNA P02545 2/20 0.36
TP53 P04637 1/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
THPO P40225 1/20 0.36
STAT6 P42226 1/20 0.36
HIF1A Q16665 1/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD11B1 P28845 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666912 0.72 MAPK1 (0.31) MAPK1NPSR1HSD11B1
SCHEMBL4439593 0.68 MAPK1 (0.38) MAPK1NPSR1LMNATP53NFKB1
SCHEMBL12763460 0.66 LMNA (0.40) MAPK1NPSR1LMNATP53NFKB1
SCHEMBL16512348 0.66 FFAR3 (0.46) MAPK1NPSR1LMNATP53NFKB1
SCHEMBL6275939 0.65 HSD11B1 (0.43) MAPK1NPSR1LMNATP53NFKB1
Biphenyl SCHEMBL2145661 0.65 ALDH1A1 (0.50) NPC1RAB9ASMN1; SMN2HSD11B1CYP3A4
Bicarbonate SCHEMBL10775900 0.64 ALDH1A1 (0.57) NPC1RAB9ASMN1; SMN2HSD11B1CYP3A4
Bicarbonate SCHEMBL7025736 0.64 ALDH1A1 (0.57) NPC1RAB9ASMN1; SMN2HSD11B1CYP3A4
Biphenyl SCHEMBL2169497 0.64 ALDH1A1 (0.57) NPC1RAB9ASMN1; SMN2HSD11B1CYP3A4
Bicarbonate SCHEMBL10581815 0.64 ALDH1A1 (0.57) NPC1RAB9ASMN1; SMN2HSD11B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090181171-A1 Method of Controlling Orientation of Domains in Block Copolymer Films INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-16 US claimed
US-20240131450-A1 CHARGED DEPTH FILTER FOR THERAPEUTIC BIOTECHNOLOGY MANUFACTURING PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-04-25 US disclosed
WO-2024025201-A1 ALIPHATIC BIFUNCTIONAL ACRYLIC MONOMER AND LOW-PERMITTIVITY COATING LIQUID COMPOSITION INCLUDING SAME 주식회사 트리엘 2024-02-01 WO disclosed
EP-4297884-A1 CHARGED DEPTH FILTER FOR THERAPEUTIC BIOTECHNOLOGY MANUFACTURING PROCESS 3M Innovative Properties Company (US) 2024-01-03 EP disclosed
EP-2845845-B1 NOVEL OXIMESTER FLUORINE COMPOUND, AND PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION COMPRISING SAME KOREA RES INST CHEMICAL TECH (KR) 2019-07-03 EP disclosed
US-10144760-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-04 US disclosed
US-9828518-B2 Copolymer formulations, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-28 US disclosed
US-9821276-B2 Nonwoven article grafted with copolymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-11-21 US disclosed
US-9481849-B2 Polymer useful as viscosity index improver EVONIK OIL ADDITIVES GMBH (DE) 2016-11-01 US disclosed
US-9463146-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-10-11 US disclosed
US-20070197410-A1 Energy efficiency in hydraulic systems ROHMAX ADDITIVES GMBH (DE) 2007-08-23 US disclosed
US-20060240999-A1 Use of a polyalkylmethacrylate polymer ROHMAX ADDITIVES GMBH (DE) 2006-10-26 US disclosed
US-7097959-B1 Negative resist composition ADMS TECHNOLOGY CO., LTD. (KR) 2006-08-29 US disclosed
US-20060173142-A1 Functionalized thermosetting resin systems REICHHOLD, INC. 2006-08-03 US disclosed
US-7074858-B2 Reactive oligomers HEILMANN STEVEN M 2006-07-11 US disclosed
US-7015286-B2 Reactive oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-21 US disclosed
US-20050136277-A1 Ultraviolet radiation cured powder coatings for stained wood AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2005-06-23 US disclosed
US-20040143059-A1 Process and apparatus for preparing emulsion polymers CELANESE EMULSIONS GMBH (DE) 2004-07-22 US disclosed
US-20040059044-A1 Oligomeric dyes and use thereof 3M INNOVATIVE PROPERTIES COMPANY 2004-03-25 US disclosed
US-20030212210-A1 Reactive oligomers 3M INNOVATIVE PROPERTIES COMPANY 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144760-B2 Ligand functional substrates PCNA, POLM, POLL MAPK1 1699/4885NPSR1 2713/4885LMNA 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.