Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL8603228 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL23734 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL8056551 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL8054070 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL2398487 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL29353083 | 0.87 | NPC1 (0.53) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL9273939 | 0.86 | NPC1 (0.52) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL10836210 | 0.86 | NPC1 (0.52) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL9301984 | 0.86 | NPC1 (0.52) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| Bumetrizole SCHEMBL6029618 | 0.86 | NPC1 (0.52) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185275-A1 | Chemical composition and method of polymerisation thereof for use on vehicle bodywork repair | INDUSTRIA CHIMICA REGGIANA I.C.R. S.P.A. | 2007-08-09 | — | — | US | disclosed |
| EP-1654325-A1 | CHEMICAL COMPOSITION AND METHOD OF POLYMERISATION THEREOF FOR USE ON VEHICLE BODYWORK REPAIR | Industria Chimica Reggiana I.C.R. S.P.A. (IT) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014721-A1 | CHEMICAL COMPOSITION AND METHOD OF POLYMERISATION THEREOF FOR USE ON VEHICLE BODYWORK REPAIR | INDUSTRIA CHIMICA REGGIANA I.C.R. S.P.A. (IT) | 2005-02-17 | — | — | WO | disclosed |