Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339148 | 0.73 | DHFR (0.39) | RAB9AKMT2AMEN1NPC1GAA | |
| SCHEMBL5376106 | 0.65 | ALDH1A1 (0.32) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL5315121 | 0.64 | GAA (0.48) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL5311385 | 0.64 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1POLBGAA | |
| SCHEMBL4265788 | 0.63 | MEN1 (0.52) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL39057 | 0.63 | MAPT (1.00) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL1459772 | 0.63 | MAPT (1.00) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL23620233 | 0.62 | MEN1 (0.65) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7758813 | 0.62 | RAB9A (0.85) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL13809404 | 0.62 | ALDH1A1 (1.00) | RAB9AKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |