Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394814 | 0.91 | SCN9A (0.43) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 | |
| SCHEMBL2906906 | 0.91 | MAPT (0.45) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 | |
| SCHEMBL1173770 | 0.85 | SCN9A (0.56) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 | |
| SCHEMBL13096065 | 0.85 | CYP3A4 (0.39) | USP14CYP3A4CYP2C19SCN9APTGDR2 | |
| SCHEMBL1174350 | 0.84 | SCN9A (0.55) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 | |
| SCHEMBL10293456 | 0.84 | ALDH1A1 (0.41) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 | |
| SCHEMBL1173428 | 0.82 | ALDH1A1 (0.44) | USP14CYP3A4CYP2C19SCN9AKDM4E | |
| SCHEMBL5197094 | 0.82 | NR1H4 (0.38) | CYP3A4CYP2C19SCN9AKDM4ECYP2C9 | |
| SCHEMBL5433925 | 0.81 | PRKCA (0.44) | CYP3A4CYP2C19SCN9ACYP2C9 | |
| SCHEMBL394368 | 0.81 | CNR2 (0.39) | CYP3A4CYP2C19SCN9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | IDO1, NAT1, AANAT | USP14 1743/4885CYP3A4 116/4885CYP2C19 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.