SCHEMBL5442008

SCHEMBL5442008

NNS(=O)(=O)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
APLNR P35414 2/20 0.37
CA9 Q16790 1/20 0.34
SGK1 O00141 1/20 0.32
LOXL2 Q9Y4K0 3/20 0.32
LOX P28300 1/20 0.32
EPHX2 P34913 1/20 0.32
BRD4 O60885 2/20 0.31
BRPF1 P55201 1/20 0.31
PGAM1 P18669 1/20 0.31
EPHX1 P07099 1/20 0.31
MMP1 P03956 1/20 0.31
MMP7 P09237 1/20 0.31
MMP12 P39900 1/20 0.31
ECE1 P42892 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5446496 0.97 APLNR (0.38) CA1CA2CA12CA7CA14
SCHEMBL26135172 0.92
SCHEMBL21815703 0.86
SCHEMBL9150326 0.86 APLNR (0.31) CA12CA7CA14APLNR
SCHEMBL17322191 0.78 CA1 (0.42) CA1CA2CA12CA7CA14
SCHEMBL30436508 0.75 GABRA1 (0.50) APLNREPHX1
SCHEMBL1649129 0.75 CA1 (0.52) CA1CA2CA12CA7CA14
SCHEMBL21943788 0.75 CA1 (0.52) CA1CA2CA12CA7CA14
SCHEMBL1648801 0.75 CA1 (0.52) CA1CA2CA12CA7CA14
SCHEMBL14462832 0.75 CA1 (0.52) CA1CA2CA12CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496577-A1 IMIDAZOPYRIDINE DERIVATIVES Piramal Life Sciences Limited (IN) 2012-09-12 EP claimed
US-12559455-B2 Compound as a UBR box domain ligand AUTOTAC INC. (KR) 2026-02-24 US disclosed
CN-115872992-B Agrocybenine alkaloid analogue, and preparation method and application thereof 江苏医药职业学院 2024-07-30 CN disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
CN-115872992-A Agrocybe alkaloid analogue and preparation method and application thereof 江苏医药职业学院 2023-03-31 CN disclosed
EP-2496577-A1 IMIDAZOPYRIDINE DERIVATIVES Piramal Life Sciences Limited (IN) 2012-09-12 EP disclosed
US-20070155924-A1 Starter systems II COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2007-07-05 US disclosed
CN-1860165-A Flame retardant compositions CIBA SC HOLDING AG (CH) 2006-11-08 CN disclosed
EP-1622945-A1 STARTER SYSTEMS II Cognis Deutschland GmbH & Co. KG (DE) 2006-02-08 EP disclosed
WO-2004099263-A1 STARTER SYSTEMS II COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2004-11-18 WO disclosed
EP-0055087-A1 Compositions and methods for producing expanded and cured polyester resin UNIROYAL, INC. (US) 1982-06-30 EP disclosed
US-4327196-A USING SULFONYL HYDRAZIDE BLOWING AGENTS, PEROXIDE CURING AGENTS FOR SIMULTANEOUS FOAMING AND CURING UNIROYAL, INC. (US) 1982-04-27 US disclosed
US-4256896-A THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES CIBA-GEIGY AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
US-4246422-A Naphtholactam dyestuffs CIBA-GEIGY AG (CH) 1981-01-20 US disclosed
US-4246410-A BENZINDOLE DYES OF YELLOW AND RED CIBA -GEIGY AKTIENGESELLSCHAFT (CH) 1981-01-20 US disclosed
US-4236007-A YELLOW SHADES ON POLYESTERS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-25 US disclosed
US-4180665-A Substituted 3-benz(cd)indol-2-(1H)-ylidene-furo[2,3-b]quinoxalin-2(3H)one dyestuffs CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-25 US disclosed
US-4159379-A Dispersion dyestuffs of the naphtholactam series CIBA-GEIGY AG (CH) 1979-06-26 US disclosed
US-4148805-A POLYESTERS, RED, YELLLOW CIBA-GEIGY AG (CH) 1979-04-10 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF CA1 4715/4885CA2 4852/4885CA12 4586/4885
US-12559455-B2 Compound as a UBR box domain ligand UBR4, UBTF, UBQLN1 CA1 4429/4885CA2 4588/4885CA12 4458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.