Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CDK7 | P50613 | 2/20 | 0.46 |
| ▸ | CCNH | P51946 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799103 | 0.83 | MCHR1 (0.62) | KDM4ELMNASMN1; SMN2MCHR1MAPK6 | |
| SCHEMBL5433478 | 0.83 | MCHR1 (0.62) | KDM4ELMNASMN1; SMN2MCHR1MAPK6 | |
| SCHEMBL5434587 | 0.83 | ATM (0.47) | KDM4ELMNASMN1; SMN2MCHR1JAK2 | |
| SCHEMBL5433640 | 0.80 | ALDH1A1 (0.56) | KDM4ELMNASMN1; SMN2CCNT1CDK9 | |
| SCHEMBL5943481 | 0.78 | MCHR1 (0.62) | KDM4ELMNASMN1; SMN2MCHR1 | |
| SCHEMBL5943477 | 0.78 | KDM4E (0.74) | KDM4ELMNASMN1; SMN2MCHR1ALDH1A1 | |
| SCHEMBL5433454 | 0.76 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL6456703 | 0.76 | KDM4E (0.75) | KDM4ELMNASMN1; SMN2CDK9CDK2 | |
| SCHEMBL6459301 | 0.76 | KDM4E (0.75) | KDM4ELMNASMN1; SMN2CDK9CDK2 | |
| Hydrochloric Acid SCHEMBL6928682 | 0.74 | KDM4E (0.73) | KDM4ELMNASMN1; SMN2CDK9CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185079-A1 | Therapeutic agents I | HTT, GRIN2A, GRIN1 | KDM4E 2659/4885LMNA 3591/4885SMN1; SMN2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.