Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114870 | 0.81 | ALDH1A1 (0.46) | GABRA1GABRB2TSHRCA12CA1 | |
| SCHEMBL12703564 | 0.80 | ESR1 (0.47) | ALDH1A1CYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL1639926 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL27918522 | 0.78 | MEN1 (0.50) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL4185219 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL27918545 | 0.76 | ALDH1A1 (0.38) | TSHRALDH1A1CYP3A4LMNAMEN1 | |
| SCHEMBL2114305 | 0.76 | CSNK2A1 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9414613 | 0.75 | GABRA1 (0.40) | GABRA1GABRB2TSHRCA12CA1 | |
| SCHEMBL8652236 | 0.74 | MYC (0.38) | TSHRCA1CA2CA9ALDH1A1 | |
| SCHEMBL17072796 | 0.74 | IRAK4 (0.49) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296332-A | Crosslinkable aqueous developable photoresist compositions and method for use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-03-22 | — | — | US | claimed |
| EP-0543761-A1 | Crosslinkable aqueous developable photoresist compositions and method for use thereof | International Business Machines Corporation (US) | 1993-05-26 | — | — | EP | claimed |
| US-8110688-B2 | Method for producing indole derivative having piperidine ring | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| EP-1880995-B1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | EISAI R&D MAN CO LTD (JP) | 2011-12-21 | — | — | EP | disclosed |
| CN-101171249-B | Process for preparing indole derivatives having piperidine ring | EISAI R&D MAN CO LTD | 2010-11-10 | — | — | CN | disclosed |
| US-20100197926-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| CN-101171249-A | Process for preparing indole derivatives having piperidine ring | EISAI R&D MAN CO LTD (JP) | 2008-04-30 | — | — | CN | disclosed |
| EP-1880995-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | Eisai R&D Management Co., Ltd. (JP) | 2008-01-23 | — | — | EP | disclosed |
| EP-0543762-B1 | Dry developable photoresist compositions and method for use thereof | IBM (US) | 2000-02-16 | — | — | EP | disclosed |
| US-5322765-A | Dry developable photoresist compositions and method for use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| US-5296332-A | Crosslinkable aqueous developable photoresist compositions and method for use thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0543761-A1 | Crosslinkable aqueous developable photoresist compositions and method for use thereof | International Business Machines Corporation (US) | 1993-05-26 | — | — | EP | disclosed |
| EP-0543762-A1 | Dry developable photoresist compositions and method for use thereof | International Business Machines Corporation (US) | 1993-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197926-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE HAVING PIPERIDINE RING | IDO2, IDO1, TPH2 | GABRA1 1164/4885GABRB2 1115/4885TSHR 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.