SCHEMBL544352

SCHEMBL544352

CN(C)c1ccc(C=C2C3=C(C=CCC3=O)c3ccccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.48
APP P05067 7/20 0.48
SNCA P37840 7/20 0.48
ALDH1A1 P00352 5/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
PDGFRB P09619 2/20 0.48
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PKM P14618 2/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 1/20 0.48
GMNN O75496 1/20 0.48
HPGD P15428 1/20 0.48
MTOR P42345 1/20 0.48
RAB9A P51151 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3033666 0.85 HPGD (0.41) MAPTALDH1A1MEN1KMT2AMAPK1
SCHEMBL136295 0.73 MAPT (0.59) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL29609334 0.72 MIF (0.70) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL1454792 0.72 MIF (0.70) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL10900576 0.71 MAOA (0.36) MAPTSNCAMEN1KMT2AMAPK1
SCHEMBL14589690 0.70 MAOB (0.66) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL28829617 0.70 MAOA (0.36) MAPTSNCAMEN1KMT2AMAPK1
SCHEMBL3569139 0.69 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL13343862 0.69 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL13343863 0.69 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304153-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, electrophotographic process cartridge RICOH COMPANY, LTD. (JP) 2012-11-06 US disclosed
US-8298734-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-10-30 US disclosed
US-8110326-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH COMPANY LIMITED (JP) 2012-02-07 US disclosed
US-20110059392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-03-10 US disclosed
EP-2000856-B1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge RICOH CO LTD (JP) 2011-02-02 EP disclosed
US-20100119964-A1 Electrophotographic photoreceptor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. 2010-05-13 US disclosed
EP-2000856-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge Ricoh Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080298840-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-12-04 US disclosed
US-7220522-B2 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2007-05-22 US disclosed
US-20040180280-A1 Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2004-09-16 US disclosed
US-4486519-A HIGH PHOTOSENSITYIVITY AND FLEXIBILITY RICOH COMPANY, LTD. (JP) 1984-12-04 US disclosed