Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279750 | 0.83 | PDE4D (0.42) | PDE4D | |
| SCHEMBL3713355 | 0.81 | HTR2A (0.33) | PDE4D | |
| SCHEMBL5439370 | 0.74 | PDE10A (0.31) | — | |
| SCHEMBL5447564 | 0.73 | MEN1 (0.30) | — | |
| SCHEMBL8640233 | 0.71 | GAA (0.48) | — | |
| SCHEMBL2972065 | 0.71 | PDE10A (0.40) | — | |
| SCHEMBL5447381 | 0.69 | IDH1 (0.35) | GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL14430549 | 0.69 | TRPV1 (0.36) | — | |
| SCHEMBL8640237 | 0.62 | ALDH1A1 (0.43) | — | |
| SCHEMBL4695611 | 0.61 | CSNK2A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20060281767-A1 | Triazoloypyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-14 | — | — | US | disclosed |
| EP-1644374-A1 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| EP-1638400-A2 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004112480-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113342-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179295-A1 | Triazolopyrimidines | QDPR, DPYD, CYP1B1 | CHRM2 287/4885CHRM4 484/4885CHRM5 349/4885 |
| US-20060281767-A1 | Triazoloypyrimidines | DPYD, TYMP, P2RX5 | CHRM2 775/4885CHRM4 1649/4885CHRM5 947/4885 |
| US-20070179162-A1 | Triazolopyrimdines | QDPR, CYP2D6, CYP1B1 | CHRM2 5/4885CHRM4 53/4885CHRM5 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.