SCHEMBL5445786

SCHEMBL5445786

CC1([SiH2])CCC2CC1C2(C)C

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11504897 0.75 LMNA (0.32) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL2826604 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL1962622 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL609515 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL221185 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL9862355 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL9862354 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL3504556 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL8241582 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
Water SCHEMBL890485 0.70 ALDH1A1 (0.36) LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028694-B2 Non-particulate organic porous material having optical resolution capability and method for manufacturing same ORGANO CORPORATION (JP) 2015-05-12 US disclosed
US-20140256834-A1 NON-PARTICULATE ORGANIC POROUS MATERIAL HAVING OPTICAL RESOLUTION CAPABILITY AND METHOD FOR MANUFACTURING SAME ORGANO CORPORATION (JP) 2014-09-11 US disclosed
US-8764979-B2 Non-particulate organic porous material having optical resolution capability and method for manufacturing same ORGANO CORPORATION (JP) 2014-07-01 US disclosed
US-20070155860-A1 macropores being interconnected forming mesopores with a radius of 0.01-100 mu m in the interconnected parts; an adsorbent for separating enantiomers in the pharmaceutical industry; homopolymer or copolymer of divinylbenzene ORGANO CORPORATION (JP) 2007-07-05 US disclosed
US-20050155927-A1 macropores being interconnected forming mesopores with a radius of 0.01-100 mu m in the interconnected parts; an adsorbent for separating enantiomers in the pharmaceutical industry; homopolymer or copolymer of divinylbenzene ORGANO CORPORATION (JP) 2005-07-21 US disclosed