SCHEMBL1962622

SCHEMBL1962622

[CH2]C1(C)CCC2CC1C2(C)C

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11504897 0.75 LMNA (0.32) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL2826604 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL9862355 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL221185 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL8241582 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL9862354 0.71 LMNA (0.37) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL5445786 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL3504556 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL609515 0.71 LMNA (0.30) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL20043533 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034364-A Silylchromium compounds and polymers as polymerization catalysts MOBIL OIL CORPORATION (US) 1991-07-23 US claimed
CN-101977664-B Removal of acids from tertiary amide solvents TATE & LYLE TECHNOLOGY LTD 2014-02-26 CN disclosed
US-8476424-B2 Removal of acids from tertiary amide solvents TATE & LYLE TECHNOLOGY LIMITED (GB) 2013-07-02 US disclosed
US-8324330-B2 Process for the preparation of a silylchromate catalyst Saudi Basic Industires Corporation (SA) 2012-12-04 US disclosed
US-20110136706-A1 ORGANOSULFONYL LATENT ACIDS FOR PETROLEUM WELL ACIDIZING ARKEMA INC. (US) 2011-06-09 US disclosed
CN-101977664-A Removal of acids from tertiary amide solvents TATE & LYLE TECHNOLOGY LTD 2011-02-16 CN disclosed
EP-2254677-A1 REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS Tate & Lyle Technology Limited (GB) 2010-12-01 EP disclosed
US-20090306317-A1 Process for the Preparation of a Silylchromate Catalyst SAUDI BASIC INDUSTRIES CORPORATION (SA) 2009-12-10 US disclosed
US-20090259034-A1 REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS TATE & LYLE TECHNOLOGY LIMITED (GB) 2009-10-15 US disclosed
WO-2009117317-A1 REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS TATE & LYLE TECHNOLOGY LTD (GB) 2009-09-24 WO disclosed
US-6833416-B2 Methods of polymerizing olefin monomers with mixed catalyst systems UNIVATION TECHNOLOGIES, LLC 2004-12-21 US disclosed
WO-2004085488-A2 METHODS OF POLYMERIZING OLEFIN MONOMERS WITH MIXED CATALYST SYSTEMS UNIVATION TECHNOLOGIES, LLC (US) 2004-10-07 WO disclosed
US-20040186250-A1 Methods of polymerizing olefin monomers with mixed catalyst systems UNIVATION TECHNOLOGIES, LLC 2004-09-23 US disclosed
EP-1003792-B1 A PROCESS FOR THE PREPARATION OF POLYETHYLENE UNION CARBIDE CHEM PLASTIC (US) 2001-12-05 EP disclosed
EP-1003792-A1 A PROCESS FOR THE PREPARATION OF POLYETHYLENE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-05-31 EP disclosed
US-6022933-A SUPPORTED REACTION PRODUCT OF A BIS-TRIHYDROCARBYLSILYL CHROMATE AND A HYDROCARBYLALUMINUM COMPOUND OR A HYDROCARBYL BORON COMPOUND IN A FLUIDIZED BED REACTOR HAVING A RECYCLE GAS LINE; HIGH DENSITY ETHYLENE-OLEFIN COPOLYMER UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-02-08 US disclosed
WO-1999009075-A1 A PROCESS FOR THE PREPARATION OF POLYETHYLENE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-02-25 WO disclosed
US-5034364-A Silylchromium compounds and polymers as polymerization catalysts MOBIL OIL CORPORATION (US) 1991-07-23 US disclosed
US-4065612-A CHROMATE ON SILICA SUPPORT UNION CARBIDE CORPORATION (US) 1977-12-27 US disclosed
US-3956255-A REACTION PRODUCT OF VANADIUM COMPOUND WITH ALKYLALUMINUM ALKOXIDE, TRIALKYLALUMINUM MONSANTO COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090259034-A1 REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS ACMSD, NAAA, ABHD6 LMNA 3638/4885MAPT 1017/4885TSHR 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.